Electrochemical Synthesis of Poly(amino acid)s, Poly(amino acid)–Urethane Copolymers, and Electroconductive Poly(amino acid)–Polypyrrole Complex Films

Electrochemical Analysis of Polyamino Acids and Proteins

Polyamino acids take amyloid form

Viva the worm ike yin and yang, good things usually come at a cost. If you live longer, then you give up reproductive fitness in return. The merits of this model—termed antagonistic pleiotropy—have been argued by evolutionary biologists for half a century. Some believe that the effort of reproduction is necessarily linked to deterioration characteristic of aging. have challenged the idea by unc...

Synthesis and Biomedical Applications of Polyamino Acids

Polyamino acids are able to adopt ordered conformations, such as α-helices and β-sheets, through cooperative hydrogen bonding. These conformations impart polyamino acids with various unique properties and functions in biological environments. The development of controlled ring-opening polymerization (ROP) of α-amino acid N-carboxyanhydrides (NCAs) in the past two decades has enabled the synthes...

Cultivation of bacteria producing polyamino acids with liquid manure as carbon and nitrogen source.

Poly(gamma-D-glutamic acid) (PGA)-producing strains of Bacillus species were investigated to determine their ability to contribute to reducing the amount of ammonium nitrogen in liquid manures and their ability to convert some of the ammonium into this polyamino acid as a transient depot for nitrogen. Organisms that do these things should help solve the serious environmental problems which are ...

Novel Fmoc-polyamino acids for solid-phase synthesis of defined polyamidoamines.

A versatile solid-phase approach to sequence-defined polyamidoamines was developed. Four different Fmoc-polyamino acid building blocks were synthesized by selective protection of symmetrical oligoethylenimine precursors followed by introduction of a carboxylic acid handle using cyclic anhydrides and subsequent Fmoc-protection. The novel Fmoc-polyamino acids were used to construct polyamidoamine...